Yes! In QuickBooks, add an item with "Line Note" somewhere in the product name. It will look something like this:
In QuickBooks Online:
In QuickBooks desktop:
Note that if you set the item up as a Service, you must have configured your portal to sync Service type items from QuickBooks to the portal.
Once the item syncs to the portal, you will be able to add a Line Note to an order where you will be able to enter only a description. The note will appear on the printed/emailed order without a item number, quantity, or price.